华东导读——《英国麻醉杂志》2022年4月刊，第128卷第4期
2022-05-06 13:06:41
1.静脉使用或利多卡因表麻对丙泊酚镇静下胃肠镜操作后临床结局的影响：随机对照试验的meta分析
结果：丙泊酚镇静时静注利多卡因或利多卡因表麻可以减轻术后疼痛[-0.47, 95% CI: -0.8- -0.14]，降低术中打嗝的风险[0.51, 95% CI: 0.35-0.75]和不自主活动[0.4, 95% CI: 0.16-0.96]。静注利多卡因可减少丙泊酚用量[-0.83, 95% CI: -1.19 - -0.47]，增加内镜医生满意度[0.75, 95% CI: 0.21-1.29]，缩短复苏时间[0.83, 95% CI: -1.45 - -0.21]。
▲图1.
静注利多卡因可以减少丙泊酚用量。注：利多卡因用法：静注利多卡因1.5mg/kg，2-4mgꞏkg-1ꞏh-1维持。
▲图2.
静注利多卡因可以缩短苏醒时间。
心血管
1.结肠镜检查时丙泊酚镇静期间的低血压：回顾性探索性分析和meta分析
Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis
2.麻醉复苏室内低血压的术中预测
Intraoperative prediction of postanaesthesia care unit hypotension
3.术前贫血与择期心脏手术的结局：荷兰国家登记数据的分析
Preoperative anaemia and outcome after elective cardiac surgery: a Dutch national registry analysis
临床实践
4.静脉使用或利多卡因表麻对丙泊酚镇静下胃肠镜操作后临床结局的影响：随机对照试验的meta分析
Impact of intravenous and topical lidocaine on clinical outcomes in patients receiving propofol for gastrointestinal endoscopic procedures: a meta-analysis of randomised controlled trials
5.采用指南研究与评价工具II评估麻醉出版物中近期临床实践指南的质量
Quality of recent clinical practice guidelines in anaesthesia publications using the Appraisal of Guidelines for Research and Evaluation II instrument
6.非心脏手术患者围术期使用维生素C的有效性和安全性：随机试验的系统性评价和meta分析
Efficacy and safety of perioperative vitamin C in patients undergoing noncardiac surgery: a systematic review and meta-analysis of randomised trials
7.咪达唑仑在小鼠胰腺导管腺癌模型中显示出抗肿瘤和抗炎作用
Midazolam exhibits antitumour and anti-inflammatory effects in a mouse model of pancreatic ductal adenocarcinoma
教育
8.支持基于胜任力的医学教育的麻醉临床体验评估(ACEA)的有效性证据
Validity evidence for the Anesthesia Clinical Encounter Assessment (ACEA) tool to support competency-based medical education
产科麻醉
9.椎管内使用吗啡不能预防择期剖腹产术后慢性疼痛：随机对照试验
Intrathecal morphine does not prevent chronic postsurgical pain after elective Caesarean delivery: a randomised controlled trial
疼痛
10.阿片类药物对慢性疼痛患者癌症生存率的影响：基于人群的倾向性评分匹配的队列研究
Effect of opioids on cancer survival in patients with chronic pain: a propensity score-matched population-based cohort study
11.术后疼痛以性别依赖的方式促进大鼠C-纤维活动依赖的传导减慢并诱导热超敏反应
Postoperative pain facilitates rat C-fibre activity-dependent slowing and induces thermal hypersensitivity in a sex-dependent manner
区域麻醉
12.术中使用氯胺酮预防周围神经阻滞消退后严重反跳痛的效果评价：前瞻性随机双盲、安慰剂对照研究
Evaluation of intraoperative ketamine on the prevention of severe rebound pain upon cessation of peripheral nerve block: a prospective randomised, double-blind, placebo-controlled study
（本转发内容已经征得复旦大学附属华东医院麻醉科顾卫东主任同意）
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